Aluminum and Mercury Amalgam Reaction : videos
Aluminum and Mercury Amalgam Reaction ..
Although H2 is generated, the reduction actually involves an internal electrolytic process involving electron transfer from the metal that forms a radical carbon and subsequent hydrogen abstractions from solvent. Once complete, the reaction is worked up and product-obtained by vacuum distillation. This is Walt's preferred reduction. In "Green Light" (S.3E.4) Walt criticizes Jessie's product, derogatorily stating he probably used a platinum dioxide reduction. However, Jessie states he used "mercury aluminum amalgam" because "dioxide's too hard to keep wet," which surprises Walt.
The aluminum amalgam reduction of 2-nitroalkanols …
In reductive amination, a ketone or aldehyde is condensed with an amine to form an imine or Schiff base intermediate, which is then reduced to an amine. In this case, P2P and methylamine are condensed forming the imine; this is then reduced by adding hydrogen to methamphetamine. The steps can be performed in separate reactions or together (one-pot). In , author and former meth cook Uncle Fester discusses several possible reduction methods for reductive amination—including NaCNBH4, mercury aluminum amalgam reductions, and Hydrogen bomb using H2/PtO2 or Raney nickel . Based on several scenes referencing or depicting aluminum metal and mention of "mercury amalgam," Walt and Jesse use the former where aluminum foil is "activated" with HgCl2 to give aluminum amalgam. As Uncle Fester outlines, Walt and Jessie use a one-pot reaction where P2P, 40 percent aqueous methylamine, and alcohol are mixed with mercury amalgam—mercury amalgam reductions have a characteristic foaming cloudy grey appearance, as portrayed in the cook scene from "Hazard Pay" (S.5E.3).
i've been doing some interesting organic synthesis in …
Preparative Methods: Aluminum turnings (oil-free) are etched with dilute Sodium Hydroxide to a point of strong hydrogen evolution and the solution is decanted. The metal is washed once with water so that it retains some alkali, then treated with 0.5% Mercury(II) Chloride solution for 1–2 min, and the entire procedure is repeated. The shiny amalgamated metal is washed rapidly in sequence with water, ethanol, and ether and used at once. Aluminum amalgam (1) reacts vigorously with water with liberation of hydrogen in the amount equivalent to the amount of aluminum present and can be used to dry organic solvents (ether, ethanol).a Aluminum amalgam can be also prepared from aluminum foil, which is cut into strips ∼10 cm × 1 cm and immersed, all at once, into a 2% aqueous solution of HgCl2 for 15 s. The strips are rinsed with absolute alcohol and then with ether and cut immediately with scissors into pieces ∼1 cm square, directly into the reaction vessel.b Before immersion, each strip may be rolled into a cylinder ∼1 cm in diameter. Each cylinder is amalgamated, rinsed successively with ethanol and ether and then placed in the reaction vessel.c