Greene's Protective Groups in organic synthesis - Scribd

Giovanni Sartori was born in Casalmaggiore, Italy, in 1944. He studied chemistry at the University of Parma, where he obtained his laurea degree under the guidance of Prof. Giuseppe Casnati in 1971. In 1972, he began his career at the University of Parma, working in the group of Prof. Casnati on the regio- and stereoselective functionalization of ambidental reagents. He was promoted to Associate Professor of Organic Chemistry in 1985 and Full Professor in 1994. He is currently the Head of the “Clean Synthetic Methodologies Groups” of the University of Parma. His research interests include all aspects of the heterogeneous catalysis applied to fine chemicals and pharmaceuticals production, with particular attention to the preparation and use of supported organic (chiral) catalysts. A special area of extensive interest is also the development of new eco-compatible synthetic methods, mainly based on the exploitation of solvent-free and multicomponent reactions. He has published about 130 original studies and filed approximately 20 patents.

The Role of Protective Groups in Organic Synthesis | …

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Protective Groups in Organic Synthesis, Third Edition

The Bfp (bisfluorous chain type propanoyl) group, a novel fluorous protecting reagent, was able to be prepared easily. The Bfp group was readily introduced to carbohydrate, was removed in high yield, and was recyclable after cleavage. Use of the Bfp group made it possible to synthesize a tetrasaccharide by minimal column chromatography purification. Each synthetic intermediate was able to be easily purified by using only simple fluorous-organic solvent extraction and was monitored by NMR, mass spectroscopy, and TLC.

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