KW - Boston keratoprosthesis type I

This video demonstrates the assembly and implantation of a Type I Boston KPro (MEEI, Boston, MA). The Type I artificial cornea is incorporated into a donor corneal graft and sutured into the eye similar to a penetrating keratoplasty.

Imaging implanted keratoprostheses with anterior segment OCT and UBM.

Two eye bank corneas have had a standard, threaded Boston KPro implanted and examined afterwards.

Fabrication of a keratoprosthesis.

The anterior surface power for the pseudophakic KPro is about 43-44 diopters.

Assembly
In the operating room, the technique of assembling the threadless KPro into a corneal graft varies from that of the previous, threaded type only in the placement of the back plate.

KW - Boston keratoprosthesis type I

There are currently two artificial corneas approved for use in the United States , the AlphaCor® artificial cornea and the Dohlman-Doane or Boston Keratoprosthesis (Boston KPro). For a discussion on the AlphaCor® artificial cornea, please review the EyeRounds case entitled .

Importance of nutrition to corneal grafts when used as a carrier of the Boston Keratoprosthesis.

Boston Keratoprosthesis - YouTube

AB - Purpose: To evaluate factors that contribute to keratoplasty failure after keratolimbal allograft (KLAL) and report the outcomes of Boston keratoprosthesis type I (KPro) as salvage therapy. Methods: Retrospective noncomparative case series of 7 eyes in 7 consecutive patients with ocular surface disease and limbal stem cell deficiency treated with KPro after failed KLAL. Mechanisms of graft failure, KPro device retention rate, and preoperative and postoperative best-corrected visual acuities were studied. Results: In the studied cohort, keratoplasty graft failure occurred at an average of 9.9 months (range, 1-17 months) after KLAL. Among the 7 eyes reviewed, 4 had tube shunts, 3 of which contributed directly to endothelial graft failure. One eye failed due to fungal keratitis, 1 eye failed due to immune-mediated endothelial rejection, and 2 eyes failed due to recurrent surface disease. During an average follow-up of 585 days (19.5 months) after KPro, best-corrected visual acuity improved from a median of counting fingers CF@2ft (range, hand motions to 20/400) to a median of 20/400 (range, CF@3ft to 20/25). There was 85.7% (6 of 7) retention of implanted devices at the last follow-up, with 1 eye requiring repeat KPro for corneal melt and implant extrusion after abrupt cessation of immunosuppression. Conclusions: Despite successful KLAL outcomes and systemic immunosuppression, patients who undergo ocular surface reconstruction with KLAL are still at risk for subsequent keratoplasty failure. Keratoprosthesis is a viable salvage therapy for visual rehabilitation in these patients. Adequate immunosuppression is important in postoperative management of these patients.

T1 - Outcomes of boston keratoprosthesis implantation for failed keratoplasty after keratolimbal allograft

Boston keratoprosthesis - Wikipedia

The Boston Keratoprosthesis is made of plastic (PMMA) or titanium with excellent tissue tolerance and optical properties. It consists of three parts, which when fully assembled have the shape of a collar-button.

T1 - Outcomes of boston keratoprosthesis implantation for failed keratoplasty after keratolimbal allograft

Keratoprosthesis (Kpro) - Martin McCarthy, M.D.

When the cornea becomes diseased and vision is significantly compromised, corneal transplantation may be necessary. with donor tissue is the most common treatment for corneal opacity. However, in certain severe corneal opacities, there is a high failure rate. An alternate treatment is the Boston Keratoprosthesis (Kpro) which acts as an artificial cornea.

T1 - Boston Keratoprosthesis

The Boston KPro: Revolutionized the Field of Corneal ..

Another feared complication of the keratoprosthesis is retinal detachment. The MBTKS data revealed 5 cases of retinal detachment out of 141 cases reviewed (3.5%) (15). This number is much lower than previously reported data from Ma et al, who revealed 12% of the 110 cases reviewed resulted in retinal detachment (8).