Lab 2- Graphical Linkage Synthesis will be available on
Lecture 3 Graphical Linkage Synthesis will be available on
Linkage synthesis often divided into two part i.)type and ii.) dimensional synthesis. Both synthesis reflect to a desired motion, since the result of the syntesis is a linkage that produce the requested motion. Fig 2. shows a dimensional synthesis problem, when the arm lengths of the boom linkage are copied from the drawing (). Fig 3. displays the result of a type and dimensional synthesis of a planar linkage that defines an intermittent linear motion.
graphical Linkage Synthesis will be available on
Diketopiperazine Formation In peptide synthesis diketopiperazine formation is a notorious side-reaction at the dipeptide stage and is particularly prone to occur in Fmoc based SPPS because of its mechanism. During the base-induced deprotection of the penultimate amino acid, the liberated amino function may cleave the resin ester linkage whilst forming a piperazinedione, i.e.