Protein Synthesis Flashcards | Quizlet
Included structures to identify in a diagram of protein synthesis
The results of this study are in the December 2, 2005 issue of the journal Science, in a paper entitled
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis. Co-authoring the paper with Doudna and Nogales were Bunpote Siridechadilok and Christopher Fraser of UC Berkeley, and Richard Hall of Berkeley Lab.
the site of protein synthesis in a cell is the ____ - 8242814
Said Nogales, also a member of Berkeley Lab’s Physical Biosciences Division, “Using cryo-EM, we can reconstruct images of the entire protein ensemble to study the molecular machinery behind the protein synthesis process. We now have the tools to see how the many different parts of the molecular machinery come together.”
Protein Synthesis - Department of Chemistry
BERKELEY, CA – Scientists have uncovered key new information towards understanding the crucial first step in protein synthesis, the process by which the genetic code, harbored within DNA and copied into RNA, is translated into the production of proteins. This new information also helps to explain how viruses, such as Hepatitis C, are able to highjack protein synthesis machinery in humans for their own purposes.
The secretory pathway of protein synthesis ..
At a resolution of 30 angstroms, the cryo-EM reconstructions of Doudna and Nogales and their collaborators show eIF3 to be a particle consisting of five lobes - analogous to a head, and a pair of arms and legs. The study shows that the left arm of the eIF3 complex binds to the eukaryotic protein complex that recognizes the methylated guanosine cap at the 5’-end of the eukaryotic mRNAs (mRNA consists of a coding region sandwiched between a 5’-end and a 3’-end). By drawing the mRNA’s 5’-end cap through the ribosome entry site and towards the exit, eIF3 ensures the mRNA is properly positioned for its genetic code to be translated.