Cinnamaldehyde characteristics:

Agrichemical: In term of agrochemical application, cinnamaldehyde is used as a fungicide 46. It is proven effective on over 40 different crops is typically applied to the root systems of plants 43. Its low toxicity and well-known properties make it ideal for agriculture 47. Cinnamaldehyde is an effective insecticide, and its scent is also known to repel animals, such as cats and dogs 5, 48. It has recently been recognized as a very effective insecticide for mosquito larva with as little as 29 ppm of cinnamaldehyde of it killing half of Aedes aegypti mosquito larvae in 24 hours 5.

FIG. 1: CHEMICAL STRUCTURE OF CINNAMALDEHYDE, C9H8O

CHEMISTRY AND BIOACTIVITY OF CINNAMALDEHYDE: A NATURAL MOLECULE OF MEDICINAL IMPORTANCE

Beneficial effects of cinnamaldehyde:

Composition: Cinnamon contains essential oils and all other compounds such as cinnamic acid, cinnamaldehyde and cinnamate 20. Cinnamaldehyde is the major component comprising 85% in the essential oil and the purity of cinnamaldehyde in use is high (> 98%). Both oil and pure cinnamaldehyde are equally effective in inhibiting the growth of various microorganism such as Gram-positive and Gram-negative (E. coli) bacteria, and fungi including yeasts, filamentous molds and dermatophytes 1, 26. Their minimum inhibition concentrations (MIC) values as determined by agar dilution method varied only slightly. The MICs range of both oil and cinnamaldehyde for bacteria is large. The antimicrobial effectiveness of oil and its major constituent is comparable and almost equivalent, which suggests that the broad-spectrum antibiotic activities of oil are due to cinnamaldehyde 27.

Keyword Cinnamaldehyde | Collection of Czechoslovak ...

Synthesis and formulation: There are several methods of laboratory synthesis of cinnamaldehyde is available, however it is most economically obtained from the steam distillation of the oil of cinnamon bark 2, 28. The compound can be prepared from the related compounds such as cinnamyl alcohol, (the alcohol form of cinnamaldehyde), but the first synthesis from unrelated compounds is the aldol condensation of benzaldehyde and acetaldehyde. In the cases of Bhanage et al., 1999, methyl-trans-cinnamaldehyde and cinnamaldehyde selectivity towards unsaturated alcohol reached 96% and 93% respectively high in supercritical carbon dioxide (scCO2) as a good solvent for selective production by hydrogenation.

Cinnamaldehyde is listed by the ...
1,8-cineole, ethyl cinnamate, ethyl ρ-methoxycinnamate, and trans-cinnamaldehyde.

2012 MIXED-ALDOL CONDENSATION Synthesis of Cinnamaldehyde I

Antimicrobial: Cinnamaldehyde is widely used as an antimicrobial which effectively act 43, 49. Researchers from the University of Illinois at Chicago have found that cinnamaldehyde/cinnamic aldehyde, when being used, it prevent oral bacterial growth by more than 50% 50. This compound is very effective against bacteria living at the back of the tongue, reducing anaerobic bacteria populations by about 43% 51. Furthermore, cinnamaldehyde is indicated in anticaries treatments as it exhibits the greatest antimicrobial potency at the concentration of 1.25-2.5 mg/ml as compared to other essential oils 50. It is reported that the edible films and coating containing antibacterial essential oil active component cinnamaldehyde, can be used to protect raw chicken pieces against bacterial contamination without adversely affecting the sensory preference of the baked wrapped chicken 52, 53.

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alpha-Methylcinnamaldehyde | 101-39-3

Physico-chemical properties: The physical properties of Cinnamaldehyde or trans-cinnamaldehyde with molecular formula C9H8O as for chemical formula is C6H5CH:CHCHO, Molar mass: 132.16 g/mol, slightly soluble in water about 1.1 g/L at 20 degrees Celsius, density: 1.05 g/mL at 25 degrees Celsius, Melting point: ≈ -7.5 degrees Celsius (18 F; 265.6 K), Boiling point: 248 degrees Celsius (478F; 521K). The product of cinnamaldehyde properly stored safely at 0-6 degrees Celsius. Then, the appearance of cinnamaldehyde is clear yellow oil liquid. The strong odor of cinnamon is determined especially in trans-cinnamaldehyde which gives sweet taste.

a PEL for cinnamaldehyde.

Cinnamaldehyde - Brief Profile - ECHA

IC50 values for theanti-proliferative activity of cinnamon methanol extract,trans-cinnamaldehyde and cisplatin against cancer and normalcells.