In each run, about 0.8mg of the synthesized UF resin wasused.

Melamine resins are used for the manufacture of many products, including kitchenware, laminates, overlay materials, particleboards, and floor tiles. Melamine is also used in the manufacture of flame-resistant materials. These include textiles such as upholstery, firemen uniforms, thermal liners, and heat resistant gloves and aprons. Melamine and its salts are also used as fire-retardant additives in paints, plastics, and paper.

UF Resine II Synthesized at pH 1.0, F/U 1.0, 50°C

The resin is used for the preparation of hydroxamic acid. The product can be cleaved

Resins for Solid Phase Synthesis - Glycopep

This method was introduced by R.C. Sheppard in 1971. Fmoc stands for 9-Fluorenylmethoxycarbonyl which describes the Fmoc protecting group. To remove an Fmoc from a growing peptide chain, basic conditions (usually 20% piperidine in DMF) are used. Removal of side-chain protecting groups and peptide from the resin is achieved by incubating in trifluoroacetic acid (TFA). Fmoc deprotection is usually slow because the anionic nitrogen produced at the end is not a particularly favorable product, although the whole process is thermodynamically driven by the evolution of carbon dioxide. The main advantage of Fmoc chemistry is that no hydrofluoric acid is needed. It is therefore used for most routine synthesis.

Trityl resins are the most versatile resins for solid phase synthesis

When R. B. Merrifield invented SPPS in 1963, it was according to the tBoc method. t-Boc (or Boc) stands for tert-Butyloxycarbonyl. To remove Boc from a growing peptide chain, acidic conditions are used (usually neat TFA). Removal of side-chain protecting groups and the peptide from the resin at the end of the synthesis is achieved by incubating in hydrofluoric acid (which can be dangerous); for this reason Boc chemistry is generally disfavored. However for complex syntheses Boc is favourable. When synthesizing nonnatural peptide analogs which are base-sensitive (such as depsi-peptides), Boc is necessary.

The resin is used for the preparation of acyl hydrazides and alkyl hydrazones.

CDNA Synthesis Kits | Life Science Research | Bio-Rad

Currently, two protective groups (Fmoc, Boc) are commonly used in solid-phase peptide synthesis. Their lability is caused by the carbamate group which readily releases CO2 for an irreversible decoupling step.

Pyridine synthesis - Organic chemistry

Before the Fmoc group became popular, the Boc group was commonly used for protecting the terminal amine of the peptide, requiring the use of more acid stable groups for side chain protection in orthogonal strategies. It retains usefulness in reducing aggregation of peptides during synthesis. Boc groups can be added to amino acids with boc anhydride and a suitable base.

solid phase peptide synthesis | resin manufacturers in india

This too is a useful and versatile resin. It seems to swell much more than polystyrene, in which case it may not be suitable for some automated synthesizers, if the wells are too small.

Synthesis of reduced graphene oxide/phenolic resin …

But, whichever cleavage reagent is preferred, it has to be washed out very carefully after Fmoc removal, the last washing must be neutral. When synthesizing large peptides the duration of Fmoc cleavage should be gradually increased. For safe removal of the deblocking reagent the resin may have to be washed more often.

What is Synthetic Resin? (with pictures) - wiseGEEK

There are two majorly used forms of SPPS - Fmoc and Boc. Unlike ribosome protein synthesis, solid-phase peptide synthesis proceeds in a C-terminal to N-terminal fashion. The N-termini of amino acid monomers is protected by these two groups and added onto a deprotected amino acid chain.